Love A.D.D.erall

At 21 they diagnosed me with AD/HD & gave me smart pills. My grades shot up & my future brightened & some said I was better. But I am numb inside of this drug. People I love become distant strangers sometimes, so proud of me for victories I didn’t earn. How do I tell them I am not what I do or have done. I’ll never be happy on this drug, but I’ll never be successful without it. If only I could Love Adderall.

Today’s Inquiry about Barr Laboratories and CorePharma LLC…and A Pharmacist’s Utterly Useless Response

This morning I went to refill my Adderall prescriptions at my University Health Care Center. I figured while I was there I’d “consult” with the pharmacist about the differences between pink and orange Adderall. Before I could talk to an actual pharmacist, I had to convince two of her minions that my query was in fact worthy the pharmacist’s time. (Why is it that wherever we go these days we have to wade through several layers of clueless assistants before earning the right to consult with someone who knows what they’re talking about?)

“Is the pharmacist here?” I asked the teeny-bopper undergrad employee, whose job duties aren’t supposed to exceed pushing cash register buttons and confirming that my face somewhat resembles the one on my Student ID Card.

“Uh…”

He did that thing people do when they’re clueless about what they’re supposed to do. In this case, that entailed swinging his head in the direction of the second least qualified individual in the room, a twenty-something guy in a dress shirt counting pills in the corner. He popped his head up and asked in a salesman’s voice, “Can I help you?”

“Are you the pharmacist?” I asked, though I knew he wasn’t.

“She’s in the back right now, sir. How can I help you?”

What is it about folks who aren’t allowed to wear white lab coats? What are they attempting to prove? They’re like high school rent-a-cops who wave around their pepper spray as if it were a flamethrower.

The Salesman was in no hurry to fetch the pharmacist, even when I made clear my extreme skepticism that he could answer it. I’m convinced this system is designed to protect the people who actually know what they’re talking about from having to interact with customers trying to find out whether or not we’re getting screwed.

When the pharmacist finally emerged, I told her about my dilemma with the 20mg Adderall: that I much prefer the generic orange Adderall (Barr Laboratories, inscribed ‘b 973’) to the generic pink Adderall (CorePharma LLC, inscribed ‘cor 135’).

She seemed astonished, as did her little helpers. They all acted as if it never before had occurred to them that different drug companies’ drugs, and their varying ingredients, might chemically affect one’s brain chemistry in different ways.

When the pharmacist realized the brand I was saying sucked (the pink Adderall) was the only one they carried, the campaign to vouch for the integrity of pink Adderall immediately got under way.  Out came the dubious misinformation.

“Well, the two brands are technically identical in terms of their compositions.”

I kind of froze, knowing her assumption was false, but realizing my seven years of anecdotal evidence would do little to refute whatever empirical journal articles she had read and believed. All I could manage was, “Really?”

“Yessir, it’s mandated by law that all generic brands of a medicine be the same as the original. They’re basically equivalent.”

I thought I saw the wannabe Salesman smirking from behind the medicine cabinet.

“To be perfectly honest,” the pharmacist added, “you’re the first customer who’s ever noticed a difference.”

“Ever? Really?”

“Yessir.”

You should read my blog, I felt like telling them. If these drugs are so similar, then why do I have over 90 comments from random strangers agreeing that they’re distinctly different? Instead I just stood there, rather unprepared, not confident enough to put what I knew about my own body up against whatever some lady who had never taken and compared the drugs herself had read in some book or been told by some drug company rep.

I felt embarrassed, even though I knew these pricks were dead wrong. The dickhead Salesman looked at me victoriously, like he’d just fucked my girlfriend. The frat guy cashier dude wasn’t even paying attention anymore.

Other students in line behind me looked annoyed. I felt like I had to salvage something, some inch of dignity.  So I walked out, rather than let then fill my prescription there and spend another month with that jittery pink garbage. Hell with that place.

Later on I’ll stop at Walgreens on my way home from campus and try to have that conversation again. Stay tuned!

49 Comments »

[...] was too polite & passive this morning with the pharmacist at my university health center. I phrased my question as a question, deferring to her authority as a uniformed [...]

  Suzanne Hayes wrote @

I thought I was going crazy until I came across your site…thank you. On Friday I spent almost 2 hours going to different pharmacys trying to find out the difference between generic and brand name adderall. It seems like every time I get my rx filld I get a different generic and they all effect me differently. I have been very curious about the brand name adderall and why it is so expensive? Another thing, why are the different generics so different in price also? Sometimes I pay $20 for my generic 20mg and I have also paid up to $80.00 for generic. If they are technically the same why are they so different in price? So Friday I broke down and bought the so called brand name and paid $208.00 at Walgreens. That is the most unknowledgable and expensive pharmacy I have ever been to. Next month I will be sure to go somewhere different. My brand name adderall that I bought at Walgreens say barr labratories on the bottle….hmmm? My boyfriends father is a doctor and convinced me that it would be worth it to pay for the brand name to see the difference. Well I don’t think it is worth $208.00 (i don’t have insurance) but it sure as hell is better than some of the generics. I am getting confused on which on of the generics is best, i’ve tried so many. Could you give me advice on a good generic 20mg lab to try? Also, did I get the real brand name (barr labratories)? Thanks for your time.

  Walgreens Boycott « Love A.D.D.erall wrote @

[...] I suspected, Walgreen’s does not carry the orange generic Adderall. Like my university health center, they’ve signed a long-term contract with CorePharma, the company that makes the shitty pink [...]

  Abomination1349 wrote @

Add me to your list of Walgreen’s boycotters….the pink generic pill is clearly inferior. It’s not even debatable.

Thanks for the time you put into this website.

  jeny wrote @

the pink ones do nothing to me

greedy evil corporations

i am never going to walgreens again

  JohnFL wrote @

To answer, as someone who works in Retail Pharma. Generics are guaranteed by the FDA to be “therapeutically equivalent.” Which isn’t a problem, but what EXACTLY is therapeutic equivalence?

Check out this link straight from the mouth of the FDA: http://www.fda.gov/cder/ob/docs/preface/ecpreface.htm#Therapeutic%20Equivalents

After reading a little bit, you’ll find that in order for a generic to be considered equivalent, the Cmax has to be at least 80% of the brand.

Browse around the FDA site they got a lot of good stuff. Sorry for the long answer but unfortunately there isnt a short one……

My commentary on it: The 20% variance isnt clinically significant, but it could account for the differences you feel when switching manuf. and the pharmacist should have been more sensitive to you question.

Cheers-

  worse than you thought wrote @

JohnFL

That’s 20% for each test. That means that it must be at least 80% as good as the brand name, but not more than 120% as good as the name brand.

Plus, there is a 5% chance that it wont even fall within those parameters.

  Jennifer wrote @

Here’s something else I learned that infuriated me the other day.

I kept prescribing my patients a certain medication (name brand) and pharmacies keep calling my office saying they don’t carry it, they were going to substitute the generic form. (It’s an antibiotic and I KNOW the name brand works better). Usually my MA’s get the call and insist to the pharmacist to order the name brand. I picked up the phone on one of these calls and the pharmacist told me he WOULD NOT order it or stock it. Long story short, contacted my wonderful pharmaceutical rep (who has a PharmD & was a pharmacist before changing careers) we were told that the chain pharmacies (CVS, Walgreen’s, Rite Aid, etc) get HUGE bonuses for dispensing generics over name brands at the end of the year! He said I need to write Brand Necessary and INSIST they order it for the patient.

Aside, I’ve even written for Vesicare (overactive bladder) which has NO GENERIC and pharmacists have dispensed the generic of ditropan because it’s “somewhat like Vesicare”.

  Sue Lind wrote @

Number one – thank God for this site, because like all the others above I have lost my mind with this. However, I am the opposite – the orange pills make me irritable and the pink pills work better. But there is an error here – the brand name Adderall (not XR) by the way are blue pills. Here’s what has happened with me – I live in Michigan so if you don’t have CVS sorry! CVS sells the orange generic pill. Walgreen’s typically sells the pink. But low and behold, they ran out the other day and I got a combo of pink and orange generics. What I have concluded is this – the orange takes longer to take effect, but lasts longer. The pink works stronger at first, but wears off quicker.

I have also heard from other people and read through my physician’s manual while at the office. You are supposed to take it on an empty stomach if you want it to work. Do not drink Coke – for some reason it breaks it down and it’s less effective. I’m a Coke addict so I have compromised by not drinking Coke before and for an hour after taking my meds. Usually I drink water which seems to help. Watch out for greasy foods when you take your meds. High in fat and greasiness leads to slower digestion. So that is all that I have to offer. I am quite sure that there is a difference in the way that the generics are made. How else can you describe the difference in size? It’s been so long since I actually have had the brand name that I am not sure if it worked or not!

However, I think it’s a total scam that they are doing this – the companies – pharmaceutical and insurance. I mean come on do you really want someone who is impulsive and can’t focus on medication that doesn’t work????

  NeeCee wrote @

OMG! No pharmacy has even instructed me on this!Its all the same generic lititure pamphlet..see I cant even spell cuz I took that fake pink version pill!!!!

  Just another # wrote @

Trust me they wont instruct you on much, except to by more drugs from them.

  M. Frederick Voorhees wrote @

Hi Sue-

Most people seem to like the orange better, though I’ve talked to several others who agree with you & prefer the pink.

There may never be a consensus about which type is better, but all of us that have taken both brands agree that that they are substantively different. And I concur EXACTLY with your assessment of the differences between pink and orange–pink is definitely quicker to take effect, and not as long lasting. Some people need and prefer the rush that the pink provide, while others (like me) would rather avoid the jitteriness.

What most infuriates me is not that I find the pink CorePharma to be inferior–it still is loads better than Stratera–but that the pharmaceutical companies insist that it’s equivalent to the orange Barr laboratory version. This simply is false, and for them to continue lying to patients who have taken these drugs for years is an insult to our intelligence, and dangerous. We have the right to know the truth about what we’re putting into our bodies.

The pharmacies need to throw out these shady back-room deals they’ve signed with the drug manufacturers. These are two DIFFERENT medications. Instead of passing them off as identical in order to keep corporate promises, CVS and Walgreens should honor our right to choose one OVER the other, the same way we choose Adderall over Ritalin, Concerta, Stratera, etc.

Btw, you are both right and wrong about the brand name pills being blue. It depends on the size. I take the 20mg pills, and that’s what I’ve been writing about. For doses between 12.5mg and 30mg, the brand name pills are orange. For smaller doses, which I guess you take, both the brand name and the generics are blue.

See the link below for pictures of the different brand name pills and their different sizes:

http://www.wcdtf.org/prescrip_stimulants.html

  mahendra wrote @

hi all
I am a formulation developmentscientist in a generic compony.
Every one seems to be right at there part, have good querys.
I would like to put some light on the issue.
We try to develop formulation as per the brand (it is not necessary as per fda that it should have a smae colour or shape, but it is good for patient complience to have same color), it is fda requirment that the generic should be BIOEQUIVALENT to the brand, that means it should act or have same drug blood concentration as that of brand when taken orally. So every generic manufacturer before fda approval have to produce bioequivalance data on volenters (might range from 25 to 100 example)….
so guys the generic drug is simila to brand when taken in our body……
Generic product help people to get same effect drug in less price……..
hope it answered u r questions…
let me know if any more

  NeeCee wrote @

Can I suggest an easy way to help you understand my concerns about generics? You state the generic ” should act ..the same…as that of the brand”…well…when buying a clothing garment..does the generic label fit the body the same as the designer garment…it looks somewhat the same..it may sort of hang on the body… the same..kind of..well… the generic garment usually is cheaper ..by price AND by how its made to fit each person body…Are you stating your designer drugs are the same as your generics???

  Just another # wrote @

I thought I was being neurotic when I started the generic BARR ADDERALL XR. I have been taking adderall for 11 years I never had a side effect. This so called equivalent is killing me. Shortness of breath, massive internal jitters, top of the head pain, fatigue, and brain cloudiness. I am unable to take the stuff. And because of the policies of the insurance company and there dictation on what drugs the Doctor can prescribe. Yes my doctor can right no generic, however I have to pay the cost. Now I have a full bottle of this garbage and I can’t take it. Generic drugs are not equivalent to the brand name. The components used to make generic adderall may be similar, however the FDA does not physically test the drug, there are only guidelines that the drug companies must follow. So my thought is what is really in the generic form, and what are they cut with. How can any drug company call this drug equivalent to the brand name. I have only these horrible side effects, and 0 therapeutic benefit.

  M. Frederick Voorhees wrote @

Hi mahendra-
It’s hard to believe that all of us would randomly reach the same conclusion (that the meds are fundamentally different) unless there was at least SOME truth to our paranoia. Are you sure Adderall gave you the real recipe and not a decoy?

I always hear that generics “help people to get same effect drug in less price” but its hard to find reliable info about how exactly that works, on a concrete level.

If they are so “equivalent” then why is one so much cheaper to produce than the other? Are generic companies legally forbidden to make & sell a product that’s exactly identical to the original brand? Or do they Choose to cut corners in order to cut costs.

The “less price” part is nice, but frankly I feel like I’m getting exactly what I’m paying for with generics. I’d rather just splurge for a drug that Works, especially if I’m stuck with the negative side effects either way.

  Mahendra wrote @

Hi
the reason it is available in less price is, brand componies have taken more then 20 years to develope and the get the molecule in the market, so ethically they have spen huge n number of money, they deserve to get it back, and ofcource they have there monopoly. Ofcource they know when there patent expires the generic componies will prepare the same formulation in less cost, rather charge more during there patent period.
We also have a phycological fundamentals in drug administration, example if a person have a headaque and if you give him a placebo tablet (without drug) 80 out of 100 people feel goo, its because of phycological phenomonon.
I can understand your flngs, but belive me friend US FDA do not allow to sell the drug (generic) unless and untill clinical trial are prefect, i mean to say bioequivalent.
It is upto people with what they are comfortable, there are still people who take brand even generic is in market. For you I will suggest take the brand, as physological feelings are in your case.
Hope this finds helpful to you.

  Just another # wrote @

I have to dis agree, I have worked in psych for over 12 years, on the inpt unit. I have witnessed on several occasions when one of the patients have been stable on a brand name drug for some time, and a generic drug is given to them, there is a change in the patient’s mental status. And I must tell you the patient does not know they are receiving a generic drug. So to blame this on psychological phenomenon is very insulting. And if you base your thinking on all these trials and the info provided by the drug companies, and FDA, then you know the drug companies test based on the guidelines of what the FDA have put in place. The FDA does not physically test the drugs, unless the drug companies pay for it. So who is really testing, and regulating these drugs???? The ones who get big bucks for selling the drugs.

  mike wrote @

i agree the pink ones are not as potent shortly after ingested; like the pink counterpart.
very good blog i was hooked.

  Kristen wrote @

Since the law says that they must be identical in terms of their compositions then why don’t we file a class action law suit? We’ve all wasted money on these useless pills that are NOT identical. Email me if you are interested.

Suzanne Hayes – Shire makes the original Adderall, not BARR. That sounds pretty shady if they sold you Adderall made by BARR for $208 – I’d check that out for sure!!!

  mahendra wrote @

Hi Guys…
The idea of law suit and all this crab wont work….
As i mentioned earlier…the FDA approves only when the product is BIO EQUIVALENT………never mind if the inactive ingrediants are not identical…the active remains the same…..
FDA only approves when the generic compony provide the bioequivalance data….(it is carried on volantrs in FDA approved CRO’s)
So guys…if you find the brand works for you then take the brand……what can I say….
Best of luck

  M. Frederick Voorhees wrote @

Hi Mahendra-

In fact, “bio-equivalency” allows for quite a bit of wiggle room, 10-20% to be exact. And that can vary in EITHER direction.

That means if 30% of the “active ingredient” from a brand name Adderall pill reaches the systemic circulation, Barr can make a pill where 50% reaches my circulatory system, while CorePharma could make one where only 10% does. So, those of us comparing pink and orange generics could be dealing with a 40% swing in terms of bioavailability.

And you’re telling us there’s no chance whatsoever that our bodies can detect such a profound disparity? Really??

One wonders whom you’re attempting to protect.

  mahendra wrote @

Hi Frederick
I am not protecting any one nether protesting any body…I am speaking the science……
In the Bioequivalence study…the test sample (in this case barr tablets) and the reference (in this case adderall) …the BE range is 80-120%…which is quite narrow…I don’t want to explain all the bioequivalence study at this point…(you guys can see the article at fda site http://www.fda.gov/cder/guidance/4964dft.pdf)…...
For your information the dose remains same for generic and the brand……….so if brand has 50% absorbed in systemic circulation the generic also should have the same….so it will lie in the window of 80-120……..
Hey guys I work as a sr scientist in formulation development in generic company…..so I know all the ware about of the formulation in generic business…….
I WROTE EARLIER>>>IT MIGHT BE A PHYSICOLOGICAL PHENEMONON >>>>>>WHERE YOU FIND GENERIC NOT WORKING AS WELL A BRAND>>>>>>>IN THAT CASE STOP USING THE GENERIC AND CONTINUE WITH THE BRAND…….
Cheers guys
Mahendra

  M. Frederick Voorhees wrote @

“I am speaking the science……”

Come on. You have to know this is about more than science. We The People depend on fellow human beings to enforce these scientific principles. It is naive to think human beings cannot be corrupted for the right price, especially in a Presidential Administration wrought with corruption, from the Justice Deptartment, to Defense, to the Dept. of Transportation. Why not the FDA?

Or what if Shire gave Barr and CorePharma the wrong recipe?

It’s astonishing that no one’s calling for an independent investigation or 2nd opinion.

We are not conspiracy theorists, Mahendra, but human beings who have taken this medication for a decade and know our bodies. Obviously, we don’t have careers in this industry, and need someone like you to step up and look into it for us. Instead you tell us to go back to the brand (which incidentally is not available OTC and costs hundreds of dollars more to order), and you play off our experiences as part of a “placebo effect.” This is not a “psychological phenomenon” as you offer. Our lives have changed, and I suspect history will judge the pharmaceutical apologists and others who are dismissive of our feedback as just as morally responsible as those that are cashing in.

  mahendra wrote @

I give up

Cheers
Mahendra

  Anonymous wrote @

You’re all fucking idiots, if I you came to the pharmacy counter bitching about this I’d tell you to get lost before I call the cops.

  M. Frederick Voorhees wrote @

Anonymous ignorant pharmacist-minion-moron:
But don’t those little signs on your counter encourage customers to ask questions?
PS-Enjoy my blog post in honor of you, and your kind.

  Ode to the Anonymous Pharmacy Clerk « Love A.D.D.erall wrote @

[...] recent comment by the boldly-named “Anonymous” demonstrates their dismissive [...]

  The Grounded Narcoleptic wrote @

I’m not sure where any of this hatred has come from. I understand that when you put medicine in your system you want to make sure it is safe and equal to what was offered before, but didn’t you originally TRUST these people to help you solve your ADD problems and help give you a chance at a ‘normal’ life??? For me, I take this medication for narcolepsy (there’s nothing else better out there) and it is quite imperative that it works, but I am not freaking out about the change.

Sure there may be corruption in the world. But when you start speaking to scientists in the human health and medicinal world like they are out to short-hand you for a couple extra bucks or are just plain evil, you have some moral issues yourself! They did not go through 8+ years of schooling to learn about human medicine or human chemistry/biochemistry just to become so easily corrupt as YOU are claiming. In fact, there is a certain humane passion one must have to go through a career path such as pharmaceuticals or medical research.

I suppose that you could blame the business side of the pharmaceutical companies, but in the era of people demanding drugs to fix everything wrong in their lives, how do you expect a pharmaceutical business to run? It is simple macroeconomics: impatient increase in demand of product = forced increase in supply of product.

Please do not reply with crazy angered responses because I simply had to get this off my chest. PS: People need to have faith in People every once and a while! And many thanks for your explanation, Mahendra!

  M. Frederick Voorhees wrote @

Hi Grounded Narc-

Yes, trusting people is nice. I trust my fellow A.D.D.ers & hundreds of patients whose experiences are identical to mine. As for the so-called “scientists”… I’m also in a grad program and understand the gimmicks of grant-writing, the reality that research funding often goes to those most willing to be “flexible” with their findings. “8+ years of schooling” only means you’re more invested in a given career path. As for the “humane passion one must have to go through a career path such as pharmaceuticals or medical research”… do you REALLY think that’s why doctors & brain scientists become doctors & brain scientists?

Your blind faith is touching… but not quite as useful as common sense. I suggest that you never google “Fen-Phen” or “Vioxx.” And especially don’t click on this letter to Congress. It’s from a “group of intimidated scientists who are trying to save people’s lives by making FDA approvals based on solid science. Instead, they’re being routinely overruled by politics and Big Pharma deception, which they know will result in the loss of human life as consumers are harmed or killed by dangerous medical devices and pharmaceuticals.” Something tells me it won’t fit well with your magical optimism.

  John wrote @

There is more to bioequivalence that blood concentration levels. See my previous post on isomers of molecules.

If the FDA is not specificying racemic content (i.e. how much of two d- and l- isomers must be present in a generic), then there is very likely a difference in the effects between variants of adderall.

It’s well established that the d- and l- versions of amphetamine salts have different effect profiles – that’s why dextroamphetamine is a prescribed pharmaceutical but levoamphetamine is not.

They’re the same drug, but one is contains the mirror image of the molecule in the other. Dextroamphetamine is the “right hand” version and Levoamphetamine is the “left hand” version.

Put your right hand on a mirror and you’ll see what I mean. The reflection looks like your left hand, and just as your left hand is different from your right hand, so the dextro and levo versions of amphetamine and the similar compounds in amphetamine differ.

As a matter of fact, levo-amphetamine is used in vicks inhalers because it has similar effects to dextro-amphetamine, i.e. it dilates bronchial and nasal passages, but the effects only last about 1/4 as long.

The levo- version is used in inhalers to prevent (or at least diminish) the incentive for people to extract the amphetamine and use it to get high.

Separating the levo- and dextro- versions of molecules is difficult, time-consuming, and expensive. If generic manufacturers can get away with not doing it it’s likely they won’t bother.

  DeeDee wrote @

I just started taking generic Adderall 20mg last month. My first Rx filled at Kroger was for the Barr orange pills. When I went back yesterday to get this month’s refill at the same Kroger, they gave me the CorePharma pink pills. I know that I am supposed to take the Barr version because my psychiatrist told me herself that she believes there are differences in the generics. She said to always get the Barr. So I looked at the Rx bottle at the pharmacy counter and it said Mfg: Barr. I paid and went on my merry way. This morning when I opened the bottle to take one, I was shocked to find the pink cor 135 pills inside! I immediately called Kroger and asked to speak to the pharmacist. She said they have always gotten Barr in the past, but this last shipment was CorePharma. I asked why my bottle was labeled “Barr” then? She said that is the only manufacturer listed in their system because they have not yet added CorePharma. She said I could bring the bottle back and they will put a new label on it. What the hell? I don’t want a new label;I want the correct pills! She said they got a new shipment in today of Barr and that I could have my Dr. write me a new Rx and get those. Problem is, my insurance will not approve another refill one day later. I cannot afford to pay out-of-pocket for a new script. The pharmacist said they can’t just take the pink pills back and exchange them with the Barr version because it is against federal law. Unbelievable! I am stuck with this substandard drug for the next month because Kroger failed to label my Rx bottle with the accurate contents. I will never again leave any pharmacy counter without opening the bottle to confirm what is actually inside. I am thoroughly disgusted by this entire experience and will search for a new pharmacy that carries Barr for future refills.

  kat wrote @

I have been going nuts trying to find a version of straight dex-sulfate that is NOT made by Barr. Everything Barr makes causes an itching allergic reaction. I’ve tried their Adderall–both brand and generic–with same itch response. I can only imagine what sub-standard preservatives or fillers they put in their drugs, but, that aside, has anyone found a generic 5mg short-acting dexadrine made by anybody else? And if so, which pharmacies carry it? Barr seems to have a monopoly on this drug now.
Thanks!

  NeeCee wrote @

I just came across this site and I just want to say I suffer along side of you guys when our concerns are blown off! Last two months, Kroger ran out of my medication!!TWICE! Then, they gave me what they had left and just said come back in a few days to get the rest. I was not told when Kroger slipped in those pink 20mg fakes ( instead of my orange) and I swear they are “sugar-pills”.. Who’s out there making sure we are protected from this fraud! If you use real Adderal or BARR medicine for ADD..then you must know we found something that brings a quality to our lives…we can focus and make functional decisions..even for only a short duration! We suffer enough using up so much mental energy just to make it thru the day! And the calming , focused effect the Adderal provides for me..IS different with generics! I need to know I will be abe to function…its sometimes the only hope I can depend on and when the med does not deliver..I feel dispair. Who really cares,right?

  MJ wrote @

an update, the Walgreens by me has JUST switched back to Barr’s this week- when I picked up, they gave me two bottles, half pinks (corepharma) and half orange (Barr). I was overjoyed that I no longer had to make a separate trip for this script only to Wal-Mart or Target, who’ve always carried Barrs, I just hope they’re back to stay.

I also have confronted the pharmacist about this issue though I knew it would be pretty useless– they basically give you the same look & speech they give for any generic-equivalency complaint, even though this is different- no one argued that the generic barrs were less effective, so it’s not a name-brand bias… anyway they blew it off, but something must’ve happened for Walgreens to make this switch. I’m located in WI, I don’t know if other walgreeens have also switched over yet but they should be soon since they all switched to Core at the same time, it seemed. yay for that.

  Amanda wrote @

I finally got the Barr Adderall’s of course the generics I have been wanting in the first place. I used to go to Walgreens but they suck they only carried the generic Corepharma so I just went to Walmart and they have the Barr’s never again Walgreens….

  Denise wrote @

I absolutely agree that these two generics are different. Barr allowed me to focus and have a normal day while the terrible pink pills have caused my depression to return along with severe anxiety. My doctor says she has never heard of a difference between the two but I don’t believe that for one second. I destroyed the pink pills today and now get to wait another month for the orange pills. This is BS! I will never give my business to any pharmacy that supplies these shitty sugar pills.

  Kyle wrote @

I’ve been trying to figure this out as well, I had a similar experience – just a quick note (no pun intended when you hear what I’m about to say) – There have been 2 ‘Warning’ letters from the FDA to CorePharma that certain plants may not continue to dispense the medication…to this day even and uhm well not much else was offered as to why the ‘warning’ letters were necessary but (so sorry….yeah, I’m on the pink atm) I’d defanitly take a look at FDA’s website as I did and file a complaint. I’m sorry if this doesn’t make as much sense as I really wanted to convey the irony – WalGreen’s seems dead set on sticking with a disreputable manufacturer. (aka Ranxbary , located in India -_-) I’ve already told my pharmacy any medication I need will NOT be from CorePharm, it’s my health you know ? Not just about money. Oh but don’t be so hard on CorePharm….they are happy to let you know they are trying to help the environment (?????) yeah…that’s what we look for in health care. Ridiculous.

  Kyle wrote @

…before any backlash may occurr I mention it is located in India only because it seems impossible to know who, how, where, and what the FDA is able to do outside the US… So frustrating :( I just want to worry about my health, this isn’t my job but no one is even trying to assure us with compassion – and are truly annoyed for us caring about our health. The sad part is , yeah they may be legally up to par, but it’s NOT enough. (forces myself to stop ranting) Stay safe everyone and don’t just take their word on anything, facts and proof is what’s needed on our end…the question is how ? I didn’t catch a single word Mahendra said though I noticed how quickly it didn’t matter to him/her any longer, but uhh thanks I guess…not very often a scientist stops by to blog. heh *don’t throw away the proof – it would be something the FDA can use to trace it back to specific manufacturing plant* I really tried my best to get a point across…leaving frustrated with my lack of being able to focus like I used to :(

  HERE ARE THE REAL DIFFERENCES wrote @

I got the makeup of BARR, CORE, and Brand, and there are differences!!!! I only listed the differences in them.

COR
ampetatine aspartate (MONOHYDRATE)
inactive
lactose monodydrate
pregelatinized starch
FD&C blue #2
Red D&C red #27 aluminam lake

COR has lactose (making it antiacid, molecules of water, and the starch is designed to thicken in cold water vs hot) Seems Core is making it somewhat an antiacid and diluting better then Barr, which may be increasing absorption and making it stronger, hence the speed feeling. (remember your told not to take antiacids or milk with the medicine)

BARR
no monodydrate
inactive
colloidal silicon dioxide,
compressible sugar,
corn starch,
saccharin sodium – CAN BE DANGEROUS, artificial sweetner, can cause urniary problems cancer

#1 aluminum lake vs #2 on cor
Yellow number 6 aluminum lake vs 27 cor

Barr is sweet because of the sugar and the dangerous sweetner saccharin. It has regular starch vs the better on in core, and it doesn’t have any water molecules or lactose as in the Cor.

Brandname adderall
LACTITOL, MICROCRYSTALLINE CELLULOSE, COLLOIDAL SILICON DIOXIDE, MAGNESIUM STEARATE, AND OTHER INGREDIENTS

brandname has the antiacid properties of lacitol, the microcrystalline makes it VERY dilutedable (it’s the highest quality and makes it breakdown and absorb fast, strong, and breaks down very easily.

So it seems that Corepharma is the better generic, yet I don’t understand the difference in mood vs absorption. I know Corepharma kicks in at 20 minutes vs over an hour for Barr, and that makes sense w/ it’s inactive ingredients. Not sure why Corepharma makes me super focused vs Barr not much focus.

  Kyle wrote @

actually that doesn’t explain anything – like I was told by someone else – it’s like the difference between expensive alchohol and cheap alchohol – the quality of amphetamine salts OBVIOUSLY are not the same. Nice try, though it’s clear you’re biased. I wonder if CorePharm even read the letters from the FDA <

  Kyle wrote @

Though truth be told, I don’t trust any generic anymore.

  Kyle wrote @

Last and final post – I’m tired of the argument when I think we all know how we are feeling : Would you mind referencing any of that information ? It’s odd that you’re the only person to have access to something we’ve all been searching for.

  Consumer wrote @

“..changed formula of adderall to avoid patent issues..”

  anonymous wrote @

It’s a fact. Brand name Adderall by Shire is the best but most expensive med because they had the patent and is superior to any and all generic substitutes of the drug.

Critics say these patients are “crazy” the generic Adderall is the same potency as Shire.

Too many patients who have taken both types of the same drug and dosage are continually documenting their experiences to their MDs and Pharmacies. Some people take these opinions as vaild, others don’t.

Do independent drug labs consistently perform drug assays and analysis/comparisons of generic to name brand?

  anonymous wrote @

BTW, what company makes the best generic duplicate in potency and compound compared to Shire Adderall?

  rock wrote @

Mr HERE ARE THE REAL DIFFERENCES
Lactitol is also a sugar…..please check, thats the reason Barr had also added compressible sugar which is manitol….
rwgards

  Victory? « Love A.D.D.erall wrote @

[...] I like one color pill better than another.  I guess I also  figured he’d just have the same blind faith in the pharmaceutical industries as the mindless clerks behind the counter, the difference being my doctor has the power to stop [...]

  HERE ARE THE REAL DIFFERENCES wrote @

I got the ingredients from Barr and Corepharma themselves, all you have to do is call them, and they’ll send you the ingredients via email.

Also……maybe people should clarify if they are on IR or extended. Because you can’t get shire with IR anymore, Barr makes the brand IR now, as well as generic and Corepharma makes the generic too.

Comparing the “inactive” ingredients, and researching them themselves, it seems corepharma was the closest to how the original IR worked.

I also noticed, a difference from 2 10 mg core and 1 20mg core IR’s. Both pills are the same size, so wonder what the difference is. Not like the pills are 1/2 the size or anything if less MG.

Im still in the testing phase for myself. Def feel some side effects if too much core, (heartbeat, etc, more thirst) Dextraamphetamine didn’t seem to really give side effects, but other then feeling content and some energy, not much focus.


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